Welcome to Riley Lab
Our Computational & Systems Biology, Cancer Genomics, and Molecular Biophysics research group at the University of Massachusetts Boston focuses on understanding the mechanisms of transcriptional and translational gene regulation in the cell. In addition, we study how those mechanisms go awry in gene regulatory diseases such as cancer. We also focus on biophysical sequence-to-affinity models of protein-DNA and protein-RNA interactions using high-throughput microarray and sequencing data. The results of our work can be found at our Affinity Data Bank. We also use these affinity models in a Systems Biology approach to find RBP and TF-markers of cancer phenotypes.
Professor Riley is now accepting graduate students from the following Ph.D. Programs serving as primary thesis adviser:
Also, he can serve as a co-mentor for a student in a molecular biology, biochemistry, genetics, computer science, or biophysics lab.